Fibromyalgia is a chronic condition characterised by widespread musculoskeletal pain, fatigue, sleep disturbance, and cognitive difficulties ('fibro fog'). It is thought to involve altered pain processing in the central nervous system rather than structural tissue damage. Fibromyalgia is often comorbid with depression, anxiety, and IBS, and diagnosis requires ruling out other conditions.
Common symptoms
See a doctor before self-treating — fibromyalgia diagnosis requires excluding other conditions (inflammatory arthritis, thyroid disease, lupus) that present similarly. Seek prompt assessment for new neurological symptoms or joint swelling, which are not typical of fibromyalgia.
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Aerobic Exercise
LifestyleResearch
Very strong
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Aerobic exercise is the most evidence-based treatment for fibromyalgia — with multiple RCTs showing significant reductions in pain, fatigue, and functional impairment.
Cognitive Behavioural Therapy
TherapyResearch
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CBT for fibromyalgia addresses catastrophising, fear-avoidance, and sleep-disturbing thoughts that amplify pain and disability in this central sensitisation disorder.
Mindfulness-Based Stress Reduction
TherapyResearch
Moderate
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MBSR reduces the emotional amplification of pain signals in fibromyalgia — a condition fundamentally characterised by central pain hypersensitivity — through sustained mindful attention training.
Hydrotherapy (Warm Water Exercise)
LifestyleResearch
Moderate
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Warm water exercise reduces fibromyalgia pain through buoyancy-facilitated movement in a warming, pressure-distributing environment that many fibromyalgia patients tolerate better than land-based exercise.
Sleep Optimisation
LifestyleResearch
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Non-restorative sleep is both a hallmark symptom and a major driver of fibromyalgia pain — improving sleep quality reduces pain sensitivity the following day.
Duloxetine / SNRIs
PharmaResearch
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Duloxetine (an SNRI) is one of only three FDA-approved medications for fibromyalgia, reducing pain through central pain modulation mechanisms.
Pregabalin (Lyrica)
PharmaResearch
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Pregabalin is FDA and TGA approved for fibromyalgia, reducing widespread pain and sleep disturbance through modulation of central pain processing.
Low-Dose Naltrexone
PharmaResearch
Limited
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Low-dose naltrexone (LDN, 1.5–4.5mg/day) is an off-label treatment for fibromyalgia with promising evidence for reducing pain via glial cell modulation.
Magnesium Malate
NaturalResearch
Limited
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Magnesium malate — combining magnesium with malic acid — has been specifically studied for fibromyalgia based on evidence linking magnesium deficiency and mitochondrial dysfunction to this condition.
Gentle Yoga and Tai Chi
LifestyleResearch
Moderate
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Gentle yoga and tai chi combine slow movement, breath awareness, and mindfulness in a format well tolerated by fibromyalgia patients, with specific RCT evidence for pain and function improvement.
WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
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Fibromyalgia is a chronic condition characterised by widespread musculoskeletal pain, fatigue, sleep disturbance, and cognitive difficulties ('fibro fog'). It is thought to involve altered pain processing in the central nervous system rather than structural tissue damage. Fibromyalgia is often comorbid with depression, anxiety, and IBS, and diagnosis requires ruling out other conditions.
Common symptoms
See a doctor before self-treating — fibromyalgia diagnosis requires excluding other conditions (inflammatory arthritis, thyroid disease, lupus) that present similarly. Seek prompt assessment for new neurological symptoms or joint swelling, which are not typical of fibromyalgia.
Filter by tradition:
WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Aerobic exercise is the most evidence-based treatment for fibromyalgia — with multiple RCTs showing significant reductions in pain, fatigue, and functional impairment.
Research
Very strong
0 sources reviewed
Community
—
Be the first to rate
6–12 weeks
Medium effort
Aerobic exercise increases endogenous opioid and serotonin levels, reducing central sensitisation. Improves HPA axis function dysregulated in fibromyalgia. Exercise-induced analgesia is well-established in chronic pain.
Start very gradually — fibromyalgia patients can experience post-exertional pain amplification with sudden increases in exercise. Even 10-minute walks 3x/week provides benefit initially. Progress slowly over months.
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