Biologic DMARDs (TNF inhibitors)
for Rheumatoid Arthritis
Biologic DMARDs — including TNF inhibitors (adalimumab, etanercept) and IL-6 inhibitors (tocilizumab) — are used for RA that does not adequately respond to conventional DMARDs like methotrexate.
How it works
TNF inhibitors bind and neutralise tumour necrosis factor-alpha, a primary driver of RA joint inflammation and destruction. Each biologic targets a specific component of the inflammatory cascade.
What to watch for
Prescription only — specialist management required. Significantly increase infection risk, particularly tuberculosis (TB screening mandatory before initiation). Expensive — PBS-subsidised in Australia when criteria met.
Community experience
Other remedies for Rheumatoid Arthritis
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