Glucosamine and Chondroitin
NaturalLimited
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Time to effect
8â12 weeks
Effort level
low
Category
Natural
Typical approach
Supplement / herb
How it works
Glucosamine is a precursor to proteoglycans in cartilage matrix. Chondroitin inhibits cartilage-degrading enzymes. Together they may have mild anti-inflammatory and cartilage-supportive effects.
Evidence is highly variable across trials. Most benefit seen with pharmaceutical-grade glucosamine sulphate (not hydrochloride) at 1500mg/day. GAIT trial showed combination beneficial only in moderate-severe OA subgroup. Some shellfish allergy concern with glucosamine.
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.