for Sciatica
Magnesium's NMDA antagonist activity may reduce the central sensitisation and neuropathic pain component of chronic sciatica.
How it works
Blocks NMDA glutamate receptors in spinal cord dorsal horn, reducing wind-up and central sensitisation that amplifies neuropathic pain from the compressed sciatic nerve.
What to watch for
Evidence for magnesium in sciatica specifically is limited. Most relevant for chronic sciatica with significant central sensitisation component. Should complement, not replace, primary physical treatment.
Community experience
Other remedies for Sciatica
See all 10 remedies âWikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.