Magnesium Supplementation
for Muscle Cramps
Magnesium plays a key role in muscle contraction and nerve function — deficiency is associated with muscle cramps, and supplementation may reduce nocturnal leg cramp frequency.
How it works
Magnesium competes with calcium at the neuromuscular junction, modulating muscle excitability and contraction threshold. Deficiency increases spontaneous firing that leads to cramping.
What to watch for
Evidence is mixed — strongest for nocturnal cramps, less clear for exercise-associated cramps. Glycinate or citrate forms are best absorbed. Avoid in renal impairment. Most trials use 300–450mg elemental magnesium.
Community experience
Other remedies for Muscle Cramps
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