NSAIDs for Acute Muscle Pain
for Muscle Pain
Oral NSAIDs reduce acute muscle pain and inflammation, though evidence for DOMS specifically is mixed — muscle repair may be temporarily slowed by prostaglandin inhibition.
How it works
COX inhibition reduces prostaglandin-driven nociceptor sensitisation in inflamed muscle. Anti-inflammatory effect reduces swelling and the chemical mediators driving muscle pain.
What to watch for
Short-term use for significant acute muscle injury or pain is appropriate. Avoid regular use for DOMS as prostaglandins play a role in muscle adaptation. Use lowest effective dose for shortest duration.
Community experience
Other remedies for Muscle Pain
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