Pharma
NSAIDs
for Sciatica
NSAIDs reduce the inflammatory component of sciatica — particularly in disc herniation where prostaglandins from the nucleus pulposus irritate the nerve root.
How it works
COX inhibition reduces prostaglandins released by the herniated disc material that directly sensitise and inflame the affected nerve root. Anti-inflammatory effect may reduce neural oedema.
What to watch for
More effective for acute disc-related sciatica than for sciatica from spinal stenosis or piriformis syndrome. Use for the shortest effective period. Monitor renal function with prolonged use.
Community experience
Other remedies for Sciatica
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