Omega-3 Fatty Acids (High Dose)
for Rheumatoid Arthritis
High-dose omega-3 supplementation (EPA + DHA, ≥3g/day) has multiple RCTs supporting reductions in RA joint tenderness and morning stiffness.
How it works
EPA and DHA compete with arachidonic acid, reducing the synthesis of pro-inflammatory prostaglandins (PGE2) and leukotrienes (LTB4) that drive RA joint inflammation. Reduces TNF-α and IL-1β production.
What to watch for
High doses (≥3g/day) are needed for anti-inflammatory effect in RA — lower doses used for general health are less effective. May mildly increase bleeding time. Use enteric-coated capsules to reduce fish burp.
Community experience
Other remedies for Rheumatoid Arthritis
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