Varenicline (Champix)
for Nicotine Withdrawal
Varenicline (Champix in Australia) is the most effective single pharmacological treatment for nicotine dependence, acting as a partial agonist at nicotinic receptors to reduce both cravings and the reward from smoking.
How it works
Partially activates nicotinic acetylcholine receptors (reducing withdrawal and cravings) while blocking nicotine's reinforcing effects if smoking occurs — removing the reward of lighting up.
What to watch for
Prescription only. Can cause vivid dreams, nausea (take with food), and rarely mood changes. Significant improvement on placebo; slightly more effective than bupropion. Report any mood changes to GP.
Community experience
Other remedies for Nicotine Withdrawal
See all 10 remedies →WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.