Natural
Zinc Supplementation (Oral)
for Acne
Oral zinc supplementation (zinc gluconate or zinc picolinate 30–45mg daily) to reduce acne severity through anti-inflammatory and antimicrobial effects.
How it works
Zinc inhibits 5-alpha-reductase (reducing sebum-stimulating DHT), suppresses P. acnes growth, reduces keratinocyte inflammation, and has antioxidant properties that reduce reactive oxygen species in follicles.
What to watch for
GI side effects (nausea, stomach upset) are common — take with food. Long-term high-dose zinc depletes copper. Zinc picolinate and gluconate are better tolerated than sulphate.
Community experience
Other remedies for Acne
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