Anticonvulsants (Carbamazepine for Trigeminal Neuralgia)
for Neuralgia
Carbamazepine is the first-line pharmacological treatment for trigeminal neuralgia and is effective in approximately 70% of patients initially, significantly reducing attack frequency and severity.
How it works
Blocks voltage-gated sodium channels in hyperexcitable trigeminal nerve fibres, reducing ectopic discharge frequency that produces the characteristic electric-shock pain.
What to watch for
Prescription only. Common side effects include dizziness, sedation, and nausea. Requires blood count monitoring (rare aplastic anaemia). HLA-B*1502 genetic testing recommended in South Asian/East Asian populations before starting.
Community experience
Other remedies for Neuralgia
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