WikiRemedy
Natural

Butterbur (Ze 339 extract)

for Hay Fever

A plant extract that has shown antihistamine-like effects for hay fever in clinical trials, without the sedation of first-generation antihistamines.

How it works

Petasin and isopetasin inhibit leukotriene and histamine synthesis. Anti-inflammatory effect independent of histamine receptor blockade.

What to watch for

Use only PA-free (pyrrolizidine alkaloid-free) extracts — raw butterbur contains hepatotoxic compounds. Ze 339 is the best-studied extract. Not for pregnancy or liver disease.

Community experience

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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.