Duloxetine / SNRIs
PharmaStrong
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Time to effect
2–4 weeks
Effort level
low
Category
Pharma
Typical approach
Medication
How it works
Inhibits serotonin and noradrenaline reuptake in descending pain inhibitory pathways, enhancing the brain's endogenous pain suppression system — specifically impaired in fibromyalgia.
Prescription only. Common side effects include nausea, dry mouth, and insomnia. Does not work for everyone. Not appropriate in combination with MAOIs. Gradually taper when discontinuing.
Medical guidance
This remedy requires a prescription or pharmacist consultation in Australia. Speak to your GP or pharmacist before use.
Community experiences
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.