Dupilumab (Dupixent)
for Eczema
A prescription biologic injection (administered fortnightly) for moderate-to-severe eczema that has not responded to topical treatments — the most significant advance in eczema treatment in decades.
How it works
Dupilumab blocks the IL-4 and IL-13 receptor (IL-4Rα), suppressing the Th2 immune response that drives atopic dermatitis. Reduces IgE, eosinophils, and the pruritic inflammatory cascade.
What to watch for
Requires specialist prescription and regular review. Expensive — insurance/PBS coverage varies by country. Conjunctivitis is a common side effect (20–30%). Requires fortnightly self-injection. Not for active skin infections.
Community experience
Other remedies for Eczema
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