Natural
Folate Supplementation
for Restless Legs Syndrome
Folic acid supplementation for RLS associated with folate deficiency, which can impair dopamine metabolism and worsen restless leg symptoms.
How it works
Folate is required for tetrahydrobiopterin synthesis, a cofactor in dopamine and serotonin production. Deficiency may impair dopaminergic tone in basal ganglia circuits involved in RLS.
What to watch for
Most relevant in confirmed or suspected folate deficiency (common in pregnancy, malabsorption, alcohol excess). Take with B12 to avoid masking deficiency.
Community experience
Other remedies for Restless Legs Syndrome
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