Gabapentin / Pregabalin
PharmaStrong
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Time to effect
Weeks
Effort level
low
Category
Pharma
Typical approach
Medication
How it works
Bind alpha-2-delta subunit of voltage-gated calcium channels in dorsal horn neurons, reducing calcium-dependent neurotransmitter release and decreasing neuropathic pain signalling.
Prescription only. Common side effects: sedation, dizziness, oedema, and cognitive dulling. Risk of dependence with long-term use. Evidence strongest for postherpetic neuralgia and diabetic neuropathy.
Medical guidance
This remedy requires a prescription or pharmacist consultation in Australia. Speak to your GP or pharmacist before use.
Community experiences
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.