Low-Dose Naltrexone
PharmaLimited
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Time to effect
4–8 weeks
Effort level
low
Category
Pharma
Typical approach
Medication
How it works
At low doses, naltrexone transiently blocks opioid receptors, causing a compensatory upregulation of endogenous opioids. Also modulates microglia (CNS immune cells), reducing neuroinflammation thought to contribute to fibromyalgia.
Off-label use — not TGA approved for fibromyalgia. Prescription required. Requires compounding pharmacy for the low dose. Generally well tolerated — vivid dreams in first weeks is the most common side effect. Discuss with GP.
Medical guidance
This remedy requires a prescription or pharmacist consultation in Australia. Speak to your GP or pharmacist before use.
Community experiences
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.