Pharma
Propranolol (Prevention)
for Migraine
A beta-blocker that is first-line preventive medication for frequent migraines. Typically reduces migraine frequency by 50% in responders.
How it works
Blocks beta-adrenergic receptors, reducing autonomic nervous system activity. Also inhibits cortical spreading depression, a key event in migraine pathophysiology.
What to watch for
Requires a prescription. Contraindicated in asthma, bradycardia, or heart block. Can cause fatigue and cold extremities. Do not stop abruptly — taper down.
Community experience
Other remedies for Migraine
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