Vitamin K2 (Menaquinone)
NaturalModerate
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.
Time to effect
6–12 months
Effort level
low
Category
Natural
Typical approach
Supplement / herb
How it works
Carboxylates osteocalcin, enabling it to bind calcium in bone matrix. Also reduces matrix Gla protein activity, preventing soft tissue calcification. Works synergistically with vitamin D.
Use MK-7 form (not K1 or MK-4) at 90–180mcg/day. Interacts with warfarin — avoid in patients on anticoagulants. Japanese trials using pharmacological K2 doses (45mg MK-4) show strongest fracture evidence; lower supplement doses have weaker data.
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WikiRemedy surfaces community experience, not medical advice. Always consult a qualified health professional.